Obesity

Association between body mass index and semen quality: a systematic review and meta-analysis

Int J Obes (Lond)Published Systematic review and meta-analysis

Authors' conclusion

In conclusion, obesity and overweight were significantly associated with semen quality reductions

Study context

Population
Men in studies from PubMed, Embase and Web of Science, inception to April 17, 2022; general population, infertile/subfertile and suspiciously subfertile men
Participants
71,337 men50 studies
Comparison
Overweight or obesity vs body mass index (BMI) < 25.0 kg/m²
Outcome
Semen quality (pooled weighted mean difference)

Pooled result

As reported in the abstract

Semen quality, obesity vs BMI < 25.0 kg/m² (average reduction)
Semen volume, reduction with obesity
0.24 ml
Total sperm number, reduction with obesity
19.56 × 106
Total motility, reduction with obesity
2.21%
Progressive motility, reduction with obesity
5.95%
Normal forms, reduction with obesity
1.08%
Semen volume, reduction with overweight
0.08 ml
Progressive motility, reduction with overweight
2.91%

Further pooled results

Semen quality by obesity class

Significant reductions in different classes of obesity; more pronounced in class II/III than class I

Semen quality by population subgroup

Significant reductions with obesity/overweight in general population, infertile or subfertile, and suspiciously subfertile men

Original publication

Association between body mass index and semen quality: a systematic review and meta-analysis. Int J Obes (Lond). Published 13 July 2024. doi:10.1038/s41366-024-01580-w

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