Association between body mass index and semen quality: a systematic review and meta-analysis
Authors' conclusion
In conclusion, obesity and overweight were significantly associated with semen quality reductions
Study context
- Population
- Men in studies from PubMed, Embase and Web of Science, inception to April 17, 2022; general population, infertile/subfertile and suspiciously subfertile men
- Participants
- 71,337 men50 studies
- Comparison
- Overweight or obesity vs body mass index (BMI) < 25.0 kg/m²
- Outcome
- Semen quality (pooled weighted mean difference)
Pooled result
As reported in the abstract
Semen quality, obesity vs BMI < 25.0 kg/m² (average reduction)
- Semen volume, reduction with obesity
- 0.24 ml
- Total sperm number, reduction with obesity
- 19.56 × 106
- Total motility, reduction with obesity
- 2.21%
- Progressive motility, reduction with obesity
- 5.95%
- Normal forms, reduction with obesity
- 1.08%
- Semen volume, reduction with overweight
- 0.08 ml
- Progressive motility, reduction with overweight
- 2.91%
Further pooled results
Semen quality by obesity class
- Significant reductions in different classes of obesity; more pronounced in class II/III than class I
Semen quality by population subgroup
- Significant reductions with obesity/overweight in general population, infertile or subfertile, and suspiciously subfertile men
Original publication
Association between body mass index and semen quality: a systematic review and meta-analysis. Int J Obes (Lond). Published 13 July 2024. doi:10. 1038/ s41366-024-01580-w
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