Obesity

Association of obesity with musculoskeletal health and functional mobility in females—a systematic review

Int J Obes (Lond)Published Systematic review

Authors' conclusion

The data collected revealed a direct impact of obesity on musculoskeletal health, gait, and functional mobility, especially among women.

Study context

Population
Adult females (age ≥19) in the general population; studies published January 2001–December 2023 (PubMed, Scopus, Web of Science, Cochrane Library)
Comparison
Obesity or overweight vs normal weight
Outcome
Association between obesity and musculoskeletal health (bones, joints, soft tissues) and/or functional mobility in women

Pooled result

As reported in the abstract

Musculoskeletal health, gait and functional mobility
  • Direct impact of obesity on musculoskeletal health, gait and functional mobility, especially among women
  • Strong association between obesity and musculoskeletal pain, particularly lower back pain
  • Obesity significantly alters gait biomechanics: increased plantar pressure, altered kinematic patterns, higher energy expenditure during walking
  • Higher BMI significantly impacts mobility-related limitations
  • Obesity, especially BMI >35 kg/m², adversely affects walking, stair climbing and chair rise ability

Original publication

Association of obesity with musculoskeletal health and functional mobility in females—a systematic review. Int J Obes (Lond). Published 18 September 2025. doi:10.1038/s41366-025-01881-8

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