Appetite Suppression by GLP ‐1 Receptor Agonists: Role of Delayed Gastric Emptying
Authors' conclusion
Delayed gastric emptying appears to play little direct role in appetite suppression induced by liraglutide.
Study context
- Population
- Patients with obesity
- Comparison
- Correlation of solid food gastric emptying with satiation and energy intake; liraglutide vs placebo
Methodological details16-week, randomized
- 16-week
- Randomized
Primary result
As reported in the abstract
Correlation of gastric emptying with appetitive measures · baseline and end of treatment
- In the entire cohorts at baseline and completion, gastric emptying correlated significantly with energy intake and, at baseline, with one parameter of satiation
- Gastric emptying accounted for only 4%-6% of the variance in these appetitive measures
- No such correlations in the placebo or liraglutide groups alone
Further findings
Appetitive measures by gastric emptying pattern (normal, persistently delayed, transiently delayed) during liraglutide
- No differences in appetitive measures among the subgroups
Original publication
Appetite Suppression by GLP ‐1 Receptor Agonists: Role of Delayed Gastric Emptying. Obesity (Silver Spring). Published 2 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →