Albuminuria and Carotid Atherosclerosis in Type 1 Diabetes Evaluated Using Three‐Dimensional Vascular Ultrasound
Main finding · Carotid TPVResult — go to the resultAdjusted ordinal logistic regression coefficient (higher TPV category) 0.82 95% CI 0.16–1.48Authors' conclusion
Participants with type 1 diabetes had higher carotid TPV than healthy controls independent of other risk factors and higher levels of albuminuria were associated with higher carotid TPV and cPTmax in type 1 diabetes.
Study context
- Population
- Individuals with T1D (albuminuria: 110 normal, 124 moderately increased, 56 severely increased) and healthy controls; 56% men, mean (SD) age 56 (14) years
- Participants
- 350 individuals
- Exposure
- T1D vs healthy controls; severely increased vs normal albuminuria in T1D
- T1Dn = 290
- Healthy controlsn = 60reference
- Outcome
- Carotid total plaque volume (TPV) by 3D vascular US and maximal plaque thickness (cPTmax) by 2D vascular US, analysed in four categories (ordinal logistic regression)
Main finding
Carotid TPV
Adjusted ordinal logistic regression coefficient (higher total plaque volume (TPV) category)
0.82
95% CI 0.16–1.48
P = 0.015
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Carotid cPTmax
| Outcome | Adjusted ordinal logistic regression coefficient (higher TPV category) (95% CI) | P value |
|---|---|---|
| Carotid TPV category: severely increased vs normal albuminuria (T1D) | 1.40 (0.61–2.21) | P < 0.001 |
Carotid cPTmax
- No difference in cPTmax category in adjusted models
Carotid TPV category: severely increased vs normal albuminuria (T1D)
- No difference for cPTmax categories
Higher current albuminuria and higher TPV / cPTmax category (T1D, adjusted)
- Higher TPV category
- P = 0.002
- Higher cPTmax category
- P = 0.047
Original publication
Albuminuria and Carotid Atherosclerosis in Type 1 Diabetes Evaluated Using Three‐Dimensional Vascular Ultrasound. Diabetes Obes Metab. Published 30 March 2026. doi:10.
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