Type 2 & other diabetes

Air Pollution and Diabetes Mellitus: Association and Validation in a Desert Area in China

J Clin Endocrinol MetabPublished Cross-sectional study

Authors' conclusion

Our study provides robust evidence of a correlation between prolonged exposure to air pollution and the prevalence of DM among individuals living in desert-adjacent areas. This research contributes to the expanding knowledge on the relationship between air pollution exposure and DM prevalence in desert-adjacent areas.

Study context

Population
Adults with health examination data in 2 regions in the southern Taklamakan Desert, China; 3-year average exposure 2018–2020>2.9 million adults
Exposure
Per 10 µg/m³ increase in air pollutants
Outcome
Diabetes mellitus (DM)
Methodological detailsgeneralized linear mixed models, space-time extra-trees exposure model
  • Generalized linear mixed models
  • Space-time extra-trees exposure model

Main finding

As reported in the abstract

DM per 10 µg/m³ increase in pollutant
Particulate matter (PM1): OR
1.898 (95% CI, 1.741-2.070)
PM2.5: OR
1.07 (95% CI, 1.053-1.086)
PM10: OR
1.013 (95% CI, 1.008-1.018)
CO: OR
1.009 (95% CI, 1.007-1.011)
NO2: OR
1.337 (95% CI, 1.234-1.449)

Observational data: associations, not effects.

Further findings

Susceptible subgroups

Men, age ≥50 years, lower educational attainment, nonsmokers and those not engaging in physical exercise appeared more susceptible to air pollution

Sensitivity analyses

Multiple sensitivity analyses confirmed the stability of the findings

Original publication

Air Pollution and Diabetes Mellitus: Association and Validation in a Desert Area in China. J Clin Endocrinol Metab. Published 9 April 2024. doi:10.1210/clinem/dgae219

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