Air Pollution and Diabetes Mellitus: Association and Validation in a Desert Area in China
Authors' conclusion
Our study provides robust evidence of a correlation between prolonged exposure to air pollution and the prevalence of DM among individuals living in desert-adjacent areas. This research contributes to the expanding knowledge on the relationship between air pollution exposure and DM prevalence in desert-adjacent areas.
Study context
- Population
- Adults with health examination data in 2 regions in the southern Taklamakan Desert, China; 3-year average exposure 2018–2020>2.9 million adults
- Exposure
- Per 10 µg/m³ increase in air pollutants
- Outcome
- Diabetes mellitus (DM)
Methodological detailsgeneralized linear mixed models, space-time extra-trees exposure model
- Generalized linear mixed models
- Space-time extra-trees exposure model
Main finding
As reported in the abstract
DM per 10 µg/m³ increase in pollutant
- Particulate matter (PM1): OR
- 1.898 (95% CI, 1.741-2.070)
- PM2.5: OR
- 1.07 (95% CI, 1.053-1.086)
- PM10: OR
- 1.013 (95% CI, 1.008-1.018)
- CO: OR
- 1.009 (95% CI, 1.007-1.011)
- NO2: OR
- 1.337 (95% CI, 1.234-1.449)
Observational data: associations, not effects.
Further findings
Susceptible subgroups
- Men, age ≥50 years, lower educational attainment, nonsmokers and those not engaging in physical exercise appeared more susceptible to air pollution
Sensitivity analyses
- Multiple sensitivity analyses confirmed the stability of the findings
Original publication
Air Pollution and Diabetes Mellitus: Association and Validation in a Desert Area in China. J Clin Endocrinol Metab. Published 9 April 2024. doi:10. 1210/ clinem/ dgae219
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