Long-Term Exposure to Fine Particulate Matter and Fasting Blood Glucose and Diabetes in 20 Million Chinese Women of Reproductive Age
Authors' conclusion
We found long-term PM2.5 exposure was associated with higher diabetes risk in women of reproductive age in China.
Study context
- Population
- Women aged 20–49 years in the National Free Preconception Health Examination Project, China, 2010–2015
- Participants
- 20,076,032 women
- Exposure
- Per IQR increase in 3-year average PM2.5
- Outcome
- FBG level and diabetes risk
Methodological detailssatellite-based PM2.5 estimation, multivariate linear and logistic regression
- Satellite-based PM2.5 estimation
- Multivariate linear and logistic regression
Main finding
As reported in the abstract
Increase in fasting blood glucose (FBG)
0.078 mmol/L
95% CI 0.077, 0.079
Higher risk of diabetes
18%
95% CI 16%, 19%
Observational data: associations, not effects.
Further findings
Diabetes burden attributable to PM2.5 >5 μg/m³
- Attributable fraction
- 29.0% (95% CI 27.5%, 30.5%)
- Additional diabetes cases
- 78.6 thousand (95% CI 74.5, 82.6 thousand)
Subgroups
- More pronounced diabetes risks in overweight or obese, age >35 years, less educated, minority ethnicity, rural household, western China
Original publication
Long-Term Exposure to Fine Particulate Matter and Fasting Blood Glucose and Diabetes in 20 Million Chinese Women of Reproductive Age. Diabetes Care. Published 22 May 2024. doi:10.
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