Newly detected diabetes mellitus patients with acute coronary syndrome have an adverse cardiometabolic profile similar to patients with prior diabetes and a more extensive ischemic myocardial insult
Authors' conclusion
ACS patients with NDDM have an adverse cardiometabolic profile similar to patients with prior DM and have more extensive myocardial insult.
Study context
- Population
- Acute coronary syndrome (ACS) patients in Greece, CALLINICUS-Hellas Registry
- Participants
- 1,084 patients
- Exposure
- Newly detected diabetes mellitus (NDDM) vs non-DM vs prior DM
- Outcome
- Prevalence of NDDM
Methodological detailsmulticenter, ongoing registry
- Multicenter
- Ongoing registry
Main finding
As reported in the abstract
NDDM
6.9 %
Observational data: associations, not effects.
Further findings
| Outcome | NDDM | non-DM | P value |
|---|---|---|---|
| HDL-CNDDM vs non-DM · lower with NDDM | 38 (range 32–45) mg/dL | 42 (range 36–50) mg/dL | P < 0.05 |
| TriglyceridesNDDM vs non-DM · higher with NDDM | 144 (range 104–231) mg/dL | 115 (range 87–152) mg/dL | P < 0.05 |
| BMINDDM vs non-DM · higher with NDDM | 29.5 (range 26.4–34.3) kg/m² | 27.1 (range 24.9–29.9) kg/m² | P < 0.05 |
| Waist circumferenceNDDM vs non-DM · higher with NDDM | 107 (range 100–114) cm | 98 (range 91–106) cm | P < 0.05 |
Myocardial necrosis
- NDDM patients had more extensive myocardial necrosis than patients with prior DM
Original publication
Newly detected diabetes mellitus patients with acute coronary syndrome have an adverse cardiometabolic profile similar to patients with prior diabetes and a more extensive ischemic myocardial insult. Diabetes Res Clin Pract. Published 9 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →