Age and BMI have different effects on subcutaneous, visceral, liver, bone marrow, and muscle adiposity, as measured by computed tomography (CT) and magnetic resonance imaging (MRI)
Authors' conclusion
Age and BMI are both associated with adiposity, but their effects differ depending on the type of AT.
Study context
- Population
- Healthy, community-dwelling Chinese individuals aged 22 to 83 years
- Participants
- 400 participants
- Exposure
- Men vs Women
- Menn = 168
- Womenn = 232
- Outcome
- Associations of age and BMI with AT depots (CT and MRI PDFF)
Methodological detailscommunity-dwelling cohort
- Community-dwelling cohort
Main finding
As reported in the abstract
- Strong or very strong correlations with BMI for total adipose tissue (AT), visceral AT (VAT) and subcutaneous AT (SAT) in both sexes
- Bone marrow AT (BMAT) and erector spinae (ES) proton density fat fraction (PDFF) strongly correlated with age in women and moderately in men
- In both sexes, BMAT PDFF correlated only with age, not with other AT depots
- Psoas PDFF correlated only with ES PDFF, not with age or other AT depots
- Liver PDFF correlated with BMI and VAT and weakly with SAT in men
- VAT and SAT correlated with age and each other in both sexes
Observational data: associations, not effects.
Further findings
BMI categories
- Men: normal BMI (<24.0 kg/m²)
- 29%
- Men: overweight (24.0-27.9 kg/m²)
- 47%
- Men: obesity (≥ 28.0 kg/m²)
- 24%
- Women: normal BMI
- 46%
- Women: overweight
- 32%
- Women: obesity
- 22%
Original publication
Age and BMI have different effects on subcutaneous, visceral, liver, bone marrow, and muscle adiposity, as measured by CT and MRI. Obesity (Silver Spring). Published 23 May 2024. doi:10.
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