Gestational diabetes & diabetes in pregnancy
Adjustment of Maternal Variable Rate Insulin Infusions Using Real-Time Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes
Authors' conclusion
In this retrospective analysis of CGM adjustment of maternal VRIII, we demonstrate early feasibility and considerable accuracy.
Study context
- Population
- Women with T1D during the peripartum period commenced on variable rate intravenous insulin infusion (VRIII); median age 30 (26–35) years, first HbA1c in pregnancy 57 (49–60) mmol/mol
- Participants
- 20 women
- Exposure
- Simulated continuous glucose monitoring (CGM)-adjusted VRIII vs capillary blood glucose-adjusted VRIII
- Outcome
- CGM accuracy (Dexcom G6) using point-of-care glucose-CGM matched pairs
Methodological detailsEntirely observational, with no deviation from standard clinical care
- Entirely observational, with no deviation from standard clinical care
Main finding
As reported in the abstract
Overall median absolute relative difference (CGM vs point-of-care glucose)
Overall median absolute relative difference
6.1 (1.6-17.3)%
Observational data: associations, not effects.
Further findings
Total insulin infusion rate · simulated
Original publication
Adjustment of Maternal Variable Rate Insulin Infusions Using Real-Time Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes. Diabetes Technol Ther. Published 16 February 2023. doi:10.
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