Type 2 & other diabetes

Accumulated hypertension burden on atrial fibrillation risk in diabetes mellitus: a nationwide population study

Cardiovasc DiabetolPublished Nationwide population-based cohort study

Authors' conclusion

Accumulated hypertension burden was associated with an increased risk of incident AF in patients with diabetes. Strict BP control should be emphasized for these patients.

Study context

Population
Patients with DM who underwent three consecutive health examinations 2009–2012, Korean National Health Insurance Service
Participants
526,384 patients
Exposure
Accumulated hypertension burden 1–9 vs burden 0
Outcome
Incident AF
Follow-up
Mean 6.7 ± 1.7 years
Methodological detailsKorean National Health Insurance Service data, three consecutive health examinations 2009–2012
  • Korean National Health Insurance Service data
  • Three consecutive health examinations 2009–2012

Main finding

As reported in the abstract

Increase in risk of incident AF vs burden 0

Burden 1 to 9 vs 0: progressively increasing risk, respectively

6%, 11%, 16%, 24%, 28%, 41%, 46%, 57%, and 67%

Cluster 1-3 vs burden 0

10%

Cluster 4-6 vs burden 0

26%

Cluster 7-9 vs burden 0

45%

Observational data: associations, not effects.

Further findings

Incident atrial fibrillation (AF), overall · mean follow-up 6.7 ± 1.7 years

Newly diagnosed AF
18,561 (3.5%)

Original publication

Accumulated hypertension burden on atrial fibrillation risk in diabetes mellitus: a nationwide population study. Cardiovasc Diabetol. Published 19 January 2023. doi:10.1186/s12933-023-01736-4

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