Effect of smoking cessation and post-cessation weight change on suicide mortality in type 2 diabetes: A nationwide cohort study
Main finding · Suicide deathResult — go to the resultHazard ratio 0.82 95 % CI 0.72–0.94Authors' conclusion
Smoking cessation was associated with a reduced risk of suicide mortality in people with T2DM. This effect persisted even among those who gained or maintained weight after quitting.
Study context
- Population
- Adults with T2D who underwent health examinations in 2015–2016, South Korean National Health Insurance Service database
- Participants
- 456,936 adults
- Exposure
- Recent smoking quitters vs current smokers
- Recent quittersn = 96,797
- Current smokersn = 360,139reference
- Outcome
- Suicide mortality
- Follow-up
- Mean 5.7 years
Methodological detailsSouth Korean National Health Insurance Service database
- South Korean National Health Insurance Service database
Main finding
Suicide death
Hazard ratio
0.82
95 % CI 0.72–0.94
Recent quittersvs Current smokers
HR 0.82 (95 % CI 0.72–0.94)
As reported in the abstract
- Total suicide deaths
- 1,397
Observational data: associations, not effects.
Further findings
| Outcome | HR (95 % CI) | |
|---|---|---|
| Suicide mortality by post-cessation weight change, quitters vs current smokersQuitters with stable weightvs Current smokers | 0.83 (0.70–0.99) | |
| Suicide mortality by post-cessation weight change, quitters vs current smokersQuitters with increased weightvs Current smokers | 0.75 (0.59–0.95) | |
| Suicide mortality by post-cessation weight change, quitters vs current smokersQuitters with significant weight lossvs Current smokersNo risk reduction | 0.96 (0.70–1.31) | |
| 0.512Hazard ratio (log scale) |
Original publication
Effect of smoking cessation and post-cessation weight change on suicide mortality in type 2 diabetes: A nationwide cohort study. Diabetes Res Clin Pract. Published 26 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →