Smoking behavior change and risk of cardiovascular disease incidence and mortality in patients with type 2 diabetes mellitus
Authors' conclusion
Smoking cessation was associated with decreased CVD incidence, and all-cause and CVD mortality among T2DM patients. However, smoking reduction was not associated with decreased risks for these.
Study context
- Population
- T2D patients who smoked, Korean National Health Insurance System
- Participants
- 349,137 patients
- Exposure
- Smoking behavior change vs sustaining
- Outcome
- CVD incidence (MI, ischemic stroke) and mortality
- Follow-up
- Median 5.1 years
Main finding
As reported in the abstract
Each group vs sustainersAdjusted hazard ratio (95% CI)
QuittersMI
0.80(0.75–0.86)
QuittersIschemic stroke
0.80(0.75–0.85)
Reducers IMI; not significant
1.03(0.94–1.13)
Reducers IIschemic stroke; not significant
1.00(0.92–1.08)
- Myocardial infarction (MI) cases (overall)
- 6,514 (1.9%)
- Ischemic stroke cases (overall)
- 7,837 (2.2%)
- Deaths (overall)
- 14,932 (4.3%)
Observational data: associations, not effects.
Further findings
- Quitters had lower all-cause and cardiovascular disease (CVD) mortality than sustainers
Original publication
Smoking behavior change and risk of cardiovascular disease incidence and mortality in patients with type 2 diabetes mellitus. Cardiovasc Diabetol. Published 29 July 2023. doi:10.
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