Effect of physical activity on incident atrial fibrillation in individuals with varying duration of diabetes: a nationwide population study
Authors' conclusion
Longer DM duration was associated with a high risk of incident AF, while increased physical activity generally reduced AF risk. Engaging in > 1,500 MET-min/week was associated with the greatest AF risk reduction in patients with longer DM duration, highlighting the potential benefits of higher activity levels for AF prevention.
Study context
- Population
- Patients with T2D who underwent the Korean National Health Insurance Service health examination in 2015–2016, grouped by diabetes mellitus (DM) duration (new onset, < 5, 5–9, ≥ 10 years); aged 59.3 ± 12.0 years, 39.8% female
- Participants
- 2,392,486 patients
- Exposure
- Physical activity levels by DM duration
- Outcome
- New-onset AF
- Follow-up
- Average 3.9 ± 0.8 years
Main finding
As reported in the abstract
Incident AF
- ≥ 1,500 metabolic equivalent task (MET)-min/week: lower incident atrial fibrillation (AF) risk with DM duration ≥ 10 years
- 15%
- ≥ 1,500 MET-min/week: lower incident AF risk with DM duration 5-9 years
- 12%
- ≥ 1,500 MET-min/week: lower incident AF risk with DM duration < 5 years
- 9%
- Interaction with DM duration
- p-for-interaction = 0.002
Observational data: associations, not effects.
Original publication
Effect of physical activity on incident atrial fibrillation in individuals with varying duration of diabetes: a nationwide population study. Cardiovasc Diabetol. Published 30 March 2024. doi:10.
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