Gestational diabetes & diabetes in pregnancy
A Healthy, Low-Carbohydrate Diet During Pregnancy Is Associated With a Reduced Risk of Gestational Diabetes Mellitus
Authors' conclusion
A healthy LCD during pregnancy characterized by high-quality carbohydrates, plant protein, and unsaturated fat was associated with a lower risk of GDM, whereas an unhealthy LCD consisting of low-quality carbohydrates, animal protein, and saturated fat was associated with a higher risk of GDM.
Study context
- Population
- Pregnant women in a prospective cohort in Wuhan, China; Gestational diabetes mellitus (GDM) screened by 75-g OGTT at 24–28 weeks
- Participants
- 2,337 women
- Exposure
- Highest vs lowest quartile of overall, healthy and unhealthy low-carbohydrate diet (LCD) scores
- Outcome
- GDM
- Follow-up
- Between 24 and 28 weeks
Main finding
As reported in the abstract
Each group vs lowest quartileEstimate (95% CI)
Highest quartile
multivariable-adjusted RR (healthy LCD score) 0.68(0.49–0.94)
Highest quartile
multivariable-adjusted RR (unhealthy LCD score) 1.52(1.11–2.08)
- Women diagnosed with GDM
- 257 (11.0%)
Observational data: associations, not effects.
Further findings
Macronutrient substitution and GDM
- Substituting high-quality for low-quality carbohydrates and animal protein, and unsaturated for saturated fat: lower risk of GDM
- 13% to 29%
Original publication
A Healthy, Low-Carbohydrate Diet During Pregnancy Is Associated With a Reduced Risk of Gestational Diabetes Mellitus. J Clin Endocrinol Metab. Published 6 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →