A Body Shape Index as a Simple Anthropometric Marker of Abdominal Obesity and Risk of Cardiovascular Events
Authors' conclusion
High ABSI is independently associated with incidence of cardiovascular events. ABSI calculation should be performed for evaluation of risk of cardiovascular events.
Study context
- Population
- Subjects from the Flow-Mediated Dilation Japan registry and Hiroshima University Vascular Function registry
- Participants
- 1,857 subjects
- Exposure
- High A Body Shape Index (ABSI) vs low ABSI
- Outcome
- First major cardiovascular events:
- Death from CVD
- Nonfatal acute coronary syndrome
- Nonfatal stroke
- Follow-up
- Median 41.6 months
Methodological detailsregistry-based, multicentre registries
- Registry-based
- Multicentre registries
Main finding
As reported in the abstract
First major cardiovascular events (multivariate analysis)
High ABSI vs Low ABSIHazard ratio (95% CI)P value
Men
2.33(1.07–5.06)
P = 0.033Women
8.33(1.06–65.49)
P = 0.044- Kaplan-Meier curves significantly different between the 2 groups (men)
- P < 0.001
- Kaplan-Meier curves significantly different between the 2 groups (women)
- P < 0.001
Observational data: associations, not effects.
Further findings
AUC of ABSI to predict first major cardiovascular events vs BMI and waist circumference
- ABSI AUC superior to BMI (men)
- P = 0.032
- ABSI AUC superior to BMI (women)
- P = 0.015
- ABSI AUC vs waist circumference (men)
- P = 0.078
- ABSI AUC superior to waist circumference (women)
- P = 0.002
Events during follow-up (all subjects) · median follow-up 41.6 months
- Died
- 56
- Died from cardiovascular causes
- 23
- Nonfatal acute coronary syndrome
- 16
- Nonfatal stroke
- 14
Original publication
A Body Shape Index as a Simple Anthropometric Marker of Abdominal Obesity and Risk of Cardiovascular Events. J Clin Endocrinol Metab. Published 25 April 2024. doi:10.
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