Adaptive thermogenesis, at the level of resting energy expenditure, after diet alone or diet plus bariatric surgery
Authors' conclusion
Weight-loss modality does not seem to modulate the magnitude of AT, at the level of REE. The greater the AT, at the level of REE, the greater the drive to eat following weight loss.
Study context
- Population
- Participants with severe obesity
- Participants
- 44 participants
- Exposure
- Very low-energy diet alone vs combined with RYGB vs SG
- Outcome
- Adaptive thermogenesis (AT) at the level of REE: significantly lower measured vs predicted REE (regression model with baseline data)
- Follow-up
- Week 11
Main finding
As reported in the abstract
AT at the level of REE (measured minus predicted REE)
Adaptive thermogenesis (AT) at the level of resting energy expenditure (REE), all participants
−121 ± 188 kcal/day
p < 0.001
Observational data: associations, not effects.
Further findings
Body weight loss · week 11
- Weight lost, all participants
- 18.4 ± 3.9 kg
Association of AT with appetite
- Larger AT associated with greater reduction in fasting ghrelin and smaller reduction in postprandial hunger and desire to eat
Original publication
Adaptive thermogenesis, at the level of resting energy expenditure, after diet alone or diet plus bariatric surgery. Obesity (Silver Spring). Published 25 April 2024. doi:10.
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