Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery
Authors' conclusion
Weight loss with SG and RYGB leads to more favorable changes in gastrointestinal hormones compared with diet alone, although ratings of appetite were reduced across all groups.
Study context
- Population
- Patients with severe obesity scheduled for sleeve gastrectomy (SG) or RYGB, and controls on a very low-energy diet
- Participants
- 15 / 14 / 15
- Exposure
- VLED plus SG or RYGB vs VLED alone
- SGn = 15
- RYGBn = 14
- Controlsn = 15reference
- Outcome
- Changes in gastrointestinal hormones and appetite ratings after similar weight loss
- Follow-up
- 10 weeks
Main finding
As reported in the abstract
- Changes in body weight/composition and level of ketosis were similar across groups
- Basal and postprandial acylated ghrelin declined significantly more in SG and RYGB vs controls
- Postprandial GLP-1 increased significantly more in SG and RYGB vs controls
- Postprandial peptide YY increased in all groups
- Overall, postprandial hunger decreased and postprandial fullness increased
- Desire to eat and prospective food consumption ratings more favorable after both surgeries vs controls
Observational data: associations, not effects.
Original publication
Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery. Obesity (Silver Spring). Published 19 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →