Weight loss as a predictor of reduced survival in patients with lung cancer: a systematic review with meta-analysis
Pooled result · Overall survivalResult — go to the resultPooled adjusted hazard ratio 1.65 95% CI 1.43–1.91Authors' conclusion
Weight loss is a significant predictor of overall survival and progression-free survival in patients with lung cancer. Weight monitoring has potential to improve prognostication of survival outcomes for these patients.
Study context
- Population
- Patients with lung cancer; PubMed, Web of Science and Embase searched up to January 15, 2024
- Participants
- 14,540 patients15 studies
- Comparison
- Weight loss vs no weight loss
- Outcome
- Overall survival and progression-free survival
Pooled result
Overall survival
Pooled adjusted hazard ratio
1.65
95% CI 1.43–1.91
Weight lossvs no weight loss
pooled aHR 1.65 (95% CI 1.43–1.91)
As reported in the abstract
Further pooled results
Progression-free survival
| Pooled aHR (95% CI) | ||
|---|---|---|
| Weight lossReduced progression-free survival | 1.40 (1.15–1.71) | |
| 0.512Pooled adjusted hazard ratio (log scale) |
Overall survival, subgroups
- Weight loss significantly predicted overall survival regardless of study design, lung cancer subtype, clinical stage, weight loss definition or length of follow-up
Original publication
Weight loss as a predictor of reduced survival in patients with lung cancer: a systematic review with meta-analysis. Int J Obes (Lond). Published 3 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →