Weight loss and body composition after compounded semaglutide treatment in a real world setting
Authors' conclusion
This study demonstrates that meaningful weight loss is achievable on semaglutide/cyanocobalamin outside of a closely controlled environment. In addition, body composition improved with losses in fat mass and gains in overall proportion of lean muscle and skeletal muscle.
Study context
- Population
- Individuals in a weight management programme at a commercial wellness studio, June 2023 to January 2024; 81F/13M, mean (SD) age 46.57 (10.60) yearsanalysed
- Participants
- 94 individuals
- Outcome
- Weight loss
- Follow-up
- 3 months
Methodological detailsreal-world setting, single-group
- Real-world setting
- Single-group
Main finding
As reported in the abstract
Average weight loss, mean (SD)
4.11 (2.77) kg
Observational data: associations, not effects.
Further findings
Weight loss percentage · 3 months
- Average weight loss, mean (SD)
- 4.57% (2.96%)
Body composition changes · 3 months
kg
- Fat mass lost
- 2.67 (2.37)
- Trunk fat mass lost
- 1.10 (1.36)
- Lean mass lost
- 1.43 (1.41)
- Skeletal muscle mass lost
- 0.88 (0.81)
- As a proportion of total weight, fat mass decreased while lean muscle mass and skeletal muscle mass increased
Original publication
Weight loss and body composition after compounded semaglutide treatment in a real world setting. Diabetes Obes Metab. Published 7 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →