Waist to height ratio as a simple tool for predicting mortality: a systematic review and meta-analysis
Authors' conclusion
Higher levels of WHtR, indicating central obesity, were associated with an increased hazard of CVD and all-cause mortality. This measure can be used in the clinical setting as a simple tool for predicting mortality.
Study context
- Population
- Cohort studies in the general population reporting HRs for waist-to-height ratio (WHtR) and all-cause and cause-specific mortality; searched PubMed, Web of Science, Scopus, Google Scholar until May 202220 studies
- Comparison
- Higher vs lower waist-to-height ratio, categorical or continuous
- Outcome
- All-cause mortality
Methodological detailsrandom effect meta-analysis, Newcastle-Ottawa quality assessment, GRADE certainty assessment, Quality assessment score of all included studies was high
- Random effect meta-analysis
- Newcastle-Ottawa quality assessment
- GRADE certainty assessment
- Quality assessment score of all included studies was high
Pooled result
As reported in the abstract
All-cause mortality, general population
Hazard ratio (95% CI)
Categorical WHtRhighestvs lowest WHtR; hazard increased by 23%
1.23(1.04–1.41)
Continuous WHtRper 1 SD increment; hazard increased by 16%
1.16(1.07–1.25)
Per 1 SD increment, as printed
Further pooled results
CVD mortality
| HR (95% CI) | ||
|---|---|---|
| Categorical WHtRHighestvs lowest WHtR; hazard increased by 39% | 1.39 (1.18–1.59) | |
| 0.512Hazard ratio (log scale) |
| Outcome | HR (95% CI) | |
|---|---|---|
| CVD mortalityContinuous WHtR · per 1 SD increment; hazard increased by 19% | 1.19 (1.07–1.31) | |
| 0.512Hazard ratio (log scale) |
Original publication
Waist to height ratio as a simple tool for predicting mortality: a systematic review and meta-analysis. Int J Obes (Lond). Published 28 September 2023. doi:10. 1038/ s41366-023-01388-0
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