Obesity

Waist to height ratio as a simple tool for predicting mortality: a systematic review and meta-analysis

Int J Obes (Lond)Published Systematic review and meta-analysis of cohort studies

Authors' conclusion

Higher levels of WHtR, indicating central obesity, were associated with an increased hazard of CVD and all-cause mortality. This measure can be used in the clinical setting as a simple tool for predicting mortality.

Study context

Population
Cohort studies in the general population reporting HRs for waist-to-height ratio (WHtR) and all-cause and cause-specific mortality; searched PubMed, Web of Science, Scopus, Google Scholar until May 202220 studies
Comparison
Higher vs lower waist-to-height ratio, categorical or continuous
Outcome
All-cause mortality
Methodological detailsrandom effect meta-analysis, Newcastle-Ottawa quality assessment, GRADE certainty assessment, Quality assessment score of all included studies was high
  • Random effect meta-analysis
  • Newcastle-Ottawa quality assessment
  • GRADE certainty assessment
  • Quality assessment score of all included studies was high

Pooled result

As reported in the abstract

All-cause mortality, general population
Hazard ratio (95% CI)
Categorical WHtRhighestvs lowest WHtR; hazard increased by 23%
1.23(1.04–1.41)
Continuous WHtRper 1 SD increment; hazard increased by 16%
1.16(1.07–1.25)

Per 1 SD increment, as printed

Further pooled results

CVD mortality

HR (95% CI)
Categorical WHtRHighestvs lowest WHtR; hazard increased by 39%1.39 (1.18–1.59)
OutcomeHR (95% CI)
CVD mortalityContinuous WHtR · per 1 SD increment; hazard increased by 19%1.19 (1.07–1.31)

Original publication

Waist to height ratio as a simple tool for predicting mortality: a systematic review and meta-analysis. Int J Obes (Lond). Published 28 September 2023. doi:10.1038/s41366-023-01388-0

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