Osteoporosis, bone & mineral

Vitamin D Metabolites Are Associated With Musculoskeletal Injury in Young Adults: A Prospective Cohort Study

J Bone Miner ResPublished Prospective cohort study

Main finding · Lower body overuse musculoskeletal injury incidenceResult — go to the resultOdds ratio 6.30 95% CI 1.89–21.2

Study context

Population
Young adults (1637 men, 530 women; aged 22.6 ± 7.5 years; BMI 24.0 ± 2.6 kg/m²; 94.3% white) in initial military training during all seasons; serum vitamin D metabolites measured in week 11,637 men · 530 women
Exposure
Vitamin D metabolite quartiles/clusters
Outcome
Incidence of lower body overuse musculoskeletal and bone stress injury
Follow-up
12 weeks of training

Main finding

As reported in the abstract

Lower body overuse musculoskeletal injury incidence

Odds ratio

6.30

95% CI 1.89–21.2

P = 0.003

Lowest clustervs Highest cluster
OR 6.30 (95% CI 1.89–21.2); P = 0.003
Sustained ≥1 overuse musculoskeletal injury
21.0%

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)P value
Lower body bone stress injury incidence · 12 weeks of trainingLowest clustervs Highest clusterAdjusted for the same covariates22.08 (3.26–149.4)P = 0.001
Lower body bone stress injury incidence — Sustained ≥1 bone stress injury
5.6%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Vitamin D Metabolites Are Associated With Musculoskeletal Injury in Young Adults: A Prospective Cohort Study. J Bone Miner Res. Published 30 August 2023. doi:10.1002/jbmr.4890

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