Visceral adipose tissue during pregnancy in women with overweight or obesity and offspring metabolic health
Primary resultResult — go to the resultDifference in birthweight 161 grams 95% CI 15–307Authors' conclusion
Maternal VAT, and particularly its change during pregnancy, may influence the fetal metabolic environment, impacting insulin availability and potentially fetal growth in healthy women with overweight or obesity.
Study context
- Population
- Pregnant women with pre-pregnancy BMI 28–45 kg/m²; MRI at gestational weeks (GW) 15, 32 and at birth
- Participants
- 119 women
- Comparison
- Maternal visceral adipose tissue (VAT) decrease vs increase from GW 15 to birth
- Primary endpoint
- Association between maternal VAT and offspring metabolic health at birth
- Follow-up
- At birth
Primary result
As reported in the abstract
Difference in birthweight
161 grams
95% CI 15–307
P = 0.031
VAT decreasevs VAT increase
difference in birthweight 161 grams (95% CI 15–307); P = 0.031
pmol/L
- Offspring insulin increase per 1 cm³ maternal VAT at GW 15
- 0.25 (95% CI, 0.03; 0.46, P = 0.026)
- Offspring insulin increase per 1 cm³ maternal VAT at birth
- 0.23 (95% CI, 0.02; 0.44, P = 0.035)
Original publication
Visceral adipose tissue during pregnancy in women with overweight or obesity and offspring metabolic health. Int J Obes (Lond). Published 25 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →