DXA ‐Measured Visceral Adipose Tissue and Accelerated Biological Aging in Middle‐Aged Adults
Authors' conclusion
VAT may represent a specific marker of accelerated biological aging, independent of lifestyle and adiposity measures.
Study context
- Population
- Middle-aged adults aged 45–69 years, Busselton Healthy Ageing StudyLeukocyte telomere length (LTL) subsample 1221
- Participants
- 4,799 adults
- Exposure
- Per 1-SD increase in DXA-derived visceral adipose tissue (VAT), by sex
- Femalesn = 2,614
- Outcome
- PhenoAgeAccel and LTL (T/S ratio) associated with DXA-measured VAT
Methodological detailssex-stratified linear regression, adjusted for chronological age and lifestyle factors
- Sex-stratified linear regression
- Adjusted for chronological age and lifestyle factors
Main finding
As reported in the abstract
PhenoAgeAccel per 1-SD increase in VAT
Observational data: associations, not effects.
Further findings
VAT mass
| Outcome | Males | Females |
|---|---|---|
| LTL per 1 SD VAT | — not stated in the abstract | −0.041 (CI −0.069–-0.013) |
— not stated in the abstract
LTL per 1 SD VAT
- In females only, higher VAT was associated with shorter LTL
Further adjustment for anthropometric and other DXA adiposity measures
- Associations mostly remained significant
Original publication
DXA ‐Measured Visceral Adipose Tissue and Accelerated Biological Aging in Middle‐Aged Adults. Obesity (Silver Spring). Published 28 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →