Obesity

Standardization of dual‐energy x‐ray visceral adipose tissue measures for comparison across clinical imaging systems

Obesity (Silver Spring)Published Method comparison study

Authors' conclusion

VAT measures can be estimated from GEHC and Hologic scans that classify individuals in a substantially similar way into metabolic risk categories, and systematic bias between the measures can be removed using simple regression equations. These findings allow for DXA VAT measures to be used in complement to other imaging modalities, regardless of whether scans used GEHC or Hologic systems.

Study context

Population
Individuals aged 18–81 years scanned on GE HealthCare (GEHC) and Hologic DXA systemsvalidation sample n = 15
Participants
114 individuals
Comparison
GEHC vs Hologic DXA visceral adipose tissue (VAT) measures
Outcome
Agreement of GEHC and Hologic VAT measures
Methodological detailsDeming regression, validation in separate sample
  • Deming regression
  • Validation in separate sample

Performance

As reported in the abstract

VAT measures highly correlated, validated in separate data set (r2)

0.97

Agreement of VAT area for metabolic risk classification (weighted κ)

0.76

Original publication

Standardization of dual‐energy x‐ray visceral adipose tissue measures for comparison across clinical imaging systems. Obesity (Silver Spring). Published 3 October 2023. doi:10.1002/oby.23885

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