Standardization of dual‐energy x‐ray visceral adipose tissue measures for comparison across clinical imaging systems
Authors' conclusion
VAT measures can be estimated from GEHC and Hologic scans that classify individuals in a substantially similar way into metabolic risk categories, and systematic bias between the measures can be removed using simple regression equations. These findings allow for DXA VAT measures to be used in complement to other imaging modalities, regardless of whether scans used GEHC or Hologic systems.
Study context
- Population
- Individuals aged 18–81 years scanned on GE HealthCare (GEHC) and Hologic DXA systemsvalidation sample n = 15
- Participants
- 114 individuals
- Comparison
- GEHC vs Hologic DXA visceral adipose tissue (VAT) measures
- Outcome
- Agreement of GEHC and Hologic VAT measures
Methodological detailsDeming regression, validation in separate sample
- Deming regression
- Validation in separate sample
Performance
As reported in the abstract
VAT measures highly correlated, validated in separate data set (r2)
0.97
Agreement of VAT area for metabolic risk classification (weighted κ)
0.76
Original publication
Standardization of dual‐energy x‐ray visceral adipose tissue measures for comparison across clinical imaging systems. Obesity (Silver Spring). Published 3 October 2023. doi:10. 1002/ oby. 23885
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