Using continuous glucose monitoring to prescribe an exercise time: a randomised controlled trial in adults with type 2 diabetes
Authors' conclusion
Prescribing exercise to target peak hyperglycemia did not improve HbA1c; however cardiometabolic health outcomes improved in both groups prescribed an exercise time compared to control. Personalizing exercise prescription by prescribing a time to exercise may be a novel approach to improve health outcomes and physical activity participation.
Study context
- Population
- Adults with T2D (HbA1c 7.2 ± 0.8 %; age 63 ± 12 y; BMI 29 ± 5 kg/m²); peak hyperglycemia time from median of 14-d habitual continuous glucose monitoring (CGM)
- Comparison
- Daily exercise timed before or after CGM-determined peak hyperglycaemia vs waitlist control
- Primary endpoint
- HbA1c
- Follow-up
- 8 weeks
Methodological detailswaitlist control, Linear mixed models compared changes across time between groups
- Waitlist control
- Linear mixed models compared changes across time between groups
Primary result
As reported in the abstract
- No intervention effect for HbA1c
Further findings
| Outcome | Estimate |
|---|---|
| 24-h peak glucose change vs CTL · 8 weeksExPeak vs CTL · significantly lowered | (95% CI −2.0 to −0.3) |
| 24-h peak glucose change vs CTL · 8 weeksNonPeak vs CTL · significantly lowered | (95% CI −2.3 to −0.6) |
| %FMD change vs CTL · 8 weeksExPeak vs CTL · increased | (95% CI 0.6–1.5) |
| %FMD change vs CTL · 8 weeksNonPeak vs CTL · increased | (95% CI 0.0–1.1) |
24-h peak glucose change vs control (CTL) · 8 weeks
- Significant group interaction for changes in 24-h peak glucose
%FMD change vs CTL · 8 weeks
- Significant group interaction for changes in %FMD
Adherence
- Adherence high in both intervention groups
- >90 %
Original publication
Using continuous glucose monitoring to prescribe an exercise time: a randomised controlled trial in adults with type 2 diabetes. Diabetes Res Clin Pract. Published 27 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →