Diabetes technology

Transitioning between automated insulin delivery systems: A focus on personalisation

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

Transitioning between AID systems can enhance glucose control and user satisfaction without compromising glycaemic stability during the adjustment period.

Study context

Population
T1D subjects who had switched between automated insulin delivery (AID) systems (MiniMedTM-780G, Diabeloop-DBLG1, Tandem-t:slim-x2TM-Control-IQTM, CamAPS-FX); age 40.8 ± 11.5 years, 73 % female, HbA1c 6.94 ± 0.68 %
Participants
96 subjects
Exposure
Before vs after switching between AID systems
Outcome
Impact of switching between AID systems on glucose control and user satisfaction
Follow-up
14 days and 3 months
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

GMI

After 14 days vs Before switch: P < 0.001 to baseline · After 3 months vs Before switch: P < 0.001 to baseline

Observational data: associations, not effects.

Further findings

OutcomeBefore switchP value
TIR 70-180 mg/dl · 14 days and 3 monthsAfter 14 days vs Before switch70.53 ± 11.43 %P < 0.001 to baseline
TIR 70-180 mg/dl · 14 days and 3 monthsAfter 3 months vs Before switchP < 0.001 to baseline
  • TIR 70-180 mg/dl: After 14 days 75.73 ± 8.33 %
  • TIR 70-180 mg/dl: After 3 months 75.65 ± 7.64 %

User satisfaction

The majority of participants reported higher satisfaction
Factors most affecting satisfaction: system size, sensor performance, control algorithm specificities

Original publication

Transitioning between automated insulin delivery systems: A focus on personalisation. Diabetes Res Clin Pract. Published 26 February 2025. doi:10.1016/j.diabres.2025.112070

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