Type 1 diabetes

Glucose Control in Type 1 Diabetes after Pancreas Transplantation: Does Automated Delivery Offer Comparable Results?

Diabetes Technol TherPublished Prospective cohort study

Authors' conclusion

Overall, compared with AID treatment, pancreas transplantation led to significantly better diabetes control parameters, with the exception of time below range.

Study context

Population
People with T1D: pancreas-kidney transplant recipients vs automated insulin delivery (AID) users
Participants
31 / 200 / 177
Exposure
Pancreas-kidney transplantation vs AID
  • Transplantn = 31
  • MiniMedn = 200reference
  • Tandemn = 177reference
Outcome
HbA1c
Follow-up
1 month after pancreas transplantation (mean ± SD: 36 ± 12 days)

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Mean glycemia · 1 month after transplantation

OutcomeTransplantMiniMedTandem
TIR · 1 month after transplantation90% (interval 86–93)72% (interval 70–74)75% (interval 73–77)

Mean glycemia · 1 month after transplantation

Significantly lower mean glycemia with transplant

TIR · 1 month after transplantation

Significantly more TIR with transplant

Time in hypoglycemia

Time in hypoglycemia did not differ significantly between the groups

Original publication

Glucose Control in Type 1 Diabetes after Pancreas Transplantation: Does Automated Delivery Offer Comparable Results? Diabetes Technol Ther. Published 25 March 2025. doi:10.1089/dia.2024.0606

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