Glucose Control in Type 1 Diabetes after Pancreas Transplantation: Does Automated Delivery Offer Comparable Results?
Authors' conclusion
Overall, compared with AID treatment, pancreas transplantation led to significantly better diabetes control parameters, with the exception of time below range.
Study context
- Population
- People with T1D: pancreas-kidney transplant recipients vs automated insulin delivery (AID) users
- Participants
- 31 / 200 / 177
- Exposure
- Pancreas-kidney transplantation vs AID
- Transplantn = 31
- MiniMedn = 200reference
- Tandemn = 177reference
- Outcome
- HbA1c
- Follow-up
- 1 month after pancreas transplantation (mean ± SD: 36 ± 12 days)
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mean glycemia · 1 month after transplantation
| Outcome | Transplant | MiniMed | Tandem |
|---|---|---|---|
| TIR · 1 month after transplantation | 90% (interval 86–93) | 72% (interval 70–74) | 75% (interval 73–77) |
Mean glycemia · 1 month after transplantation
- Significantly lower mean glycemia with transplant
TIR · 1 month after transplantation
- Significantly more TIR with transplant
Time in hypoglycemia
- Time in hypoglycemia did not differ significantly between the groups
Original publication
Glucose Control in Type 1 Diabetes after Pancreas Transplantation: Does Automated Delivery Offer Comparable Results? Diabetes Technol Ther. Published 25 March 2025. doi:10. 1089/ dia. 2024. 0606
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