Unravelling dialysis‐related dysglycaemia: Longitudinal insights from continuous glucose monitoring
Authors' conclusion
CGM revealed evolving glycaemic patterns. Early improvements in TIR were not sustained, hypoglycaemia increased modestly and the overall GRI remained unchanged. These findings support CGM-informed, individualised diabetes management, prioritising safety and stability.
Study context
- Population
- People receiving maintenance haemodialysis with CGM; mean age 63.7 years, 54.5% men
- Participants
- 125 people
- Outcome
- TIR
- Follow-up
- Baseline, 6 and 12 months
Main finding
As reported in the abstract
- Time in range (TIR) at baseline
- 51.6%
- TIR at 6 months
- 56.6%
- TIR change baseline to 6 months: mean difference 5.09%, 95% CI 1.06 to 9.12
- p = 0.014
- TIR at 12 months, not sustained
- 50.5%; p = 0.568
- TIR decline between 6 and 12 months: −6.11%, 95% CI −9.03 to −3.19
- p < 0.001
Observational data: associations, not effects.
Further findings
Time below range (TBR) · 6 to 12 months
- TBR remained low; small increase between 6 and 12 months: 1.61%, 95% CI 0.59-2.64
- P = 0.002
Time above range (TAR) and glycaemic variability (GV)
- TAR and GV unchanged across timepoints
Hypoglycaemia burden and glycaemic risk index (GRI)
- Hypoglycaemia burden increased over follow-up
- P < 0.001
- GRI showed no change
Concordance of HbA1c with CGM-derived glucose
- Baseline
- ρ = 0.39; p = 0.0001
- 12 months
- ρ = 0.59; p < 0.0001
- Moderate concordance
Original publication
Unravelling dialysis‐related dysglycaemia: Longitudinal insights from continuous glucose monitoring. Diabet Med. Published 4 May 2026. doi:10.
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