Continuous Glucose Monitoring in Adults With Diabetes Receiving Haemodialysis: Identifying Dialysis‐Specific Glycaemic Patterns and Associations With Volume Status and Intradialytic Hypoglycaemia
Authors' conclusion
CGM identifies dialysis-specific glycaemic patterns and clinically relevant associations with IDWG and intradialytic hypoglycaemia that extend beyond HbA1c.
Study context
- Population
- Adults with insulin-treated diabetes receiving maintenance haemodialysis; age 56.6 ± 14.7 years, 60% T2D, diabetes duration 24.5 ± 9.9 years, HbA1c 68 ± 19 mmol/mol [8.4% ± 1.7%]246 haemodialysis sessions
- Participants
- 40 adults
- Outcome
- CGM glycaemic patterns across the dialysis cycle
Methodological details2-week continuous glucose monitoring (CGM) assessment
- 2-week CGM assessment
Main finding
As reported in the abstract
- Time in range (TIR) (3.9-10.0 mmol/L), pre-dialytic period
- 36.1%
- TIR, intradialytic period (increase vs pre-dialytic, p < 0.001)
- 60.9%
- TIR, post-dialysis (decrease, p < 0.001)
- 17.8%
- Mean glucose reduction during dialysis
- 32%
- Mean glucose at dialysis initiation
- 11.1 ± 3.5 mmol/L
- Intradialytic nadir of mean glucose at 125 min
- 7.6 ± 2.2 mmol/L
Observational data: associations, not effects.
Further findings
Associations with interdialytic weight gain (IDWG) and recurrent intradialytic hypotension (IDH)
- Lower baseline 14-day TIR, but not HbA1c or glucose at dialysis initiation, independently associated with higher IDWG
- Higher IDWG an independent risk factor for recurrent IDH
Safety
- Participants with intradialytic hypoglycaemia
- 20.0%
- Association with higher baseline 14-day time below range (< 3.9 mmol/L), OR per 1% increase (p = 0.049)
- 2.42
Original publication
Continuous Glucose Monitoring in Adults With Diabetes Receiving Haemodialysis: Identifying Dialysis‐Specific Glycaemic Patterns and Associations With Volume Status and Intradialytic Hypoglycaemia. Diabetes Obes Metab. Published 24 April 2026. doi:10.
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