Type 1 diabetes and risk of heart failure: A systematic review and meta-analysis
Pooled result · HF incidenceResult — go to the resultAdjusted relative risk 3.4 95% CI 2.71–4.26Authors' conclusion
Individuals with T1DM had a substantially higher risk of HF compared to those without diabetes.
Study context
- Population
- Studies in PubMed and EMBASE reporting heart failure (HF) incidence and adjusted relative risk (aRR) in T1D, T2D and non-diabetic controls; pooled mean ages 40, 65 and 57 years; men 56%, 54% and 55%4 studies
- Participants
- 61,885 / 248,021 / 4,599,213
- Comparison
- T1D vs non-diabetic controls
- T1DMn = 61,885
- T2DMn = 248,021
- Controlsn = 4,599,213reference
- Outcome
- HF incidence rate and adjusted relative risk of HF
- Follow-up
- 1 to 12 years
Pooled result
HF incidence
Adjusted relative risk
3.4
95% CI 2.71–4.26
Events by group
T1DM
5.8 per 1000 person-years
1378 of 61,885
T2DM
10.0 per 1000 person-years
3993 of 248,021
Controls
2.3 per 1000 person-years
18,945 of 4,599,213
T1DMvs Controls
aRR 3.4 (95% CI 2.71–4.26)
As reported in the abstract
Further pooled results
| Outcome | aRR (95% CI) | |
|---|---|---|
| HF risk T1Dvs controls, womenWomen | 4.9 (4.1–5.9) | |
| HF risk T1Dvs controls, menMen | 3.0 (2.2–4.0) | |
| 0.20.5125Adjusted relative risk (log scale) |
Original publication
Type 1 diabetes and risk of heart failure: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 24 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →