Tripeptide gut hormone infusion does not alter food preferences or sweet taste function in volunteers with obesity and prediabetes/diabetes but promotes restraint eating: A secondary analysis of a randomized single‐blind placebo‐controlled study
Authors' conclusion
The elevation in plasma GOP concentrations after RYGB is unlikely to mediate changes in food preferences and sweet taste function after surgery but may promote restraint eating.
Study context
- Population
- Subjects with obesity and prediabetes/diabetes
- Participants
- 24 subjects
- Comparison
- Subcutaneous GLP-1, oxyntomodulin (OXM) and PYY infusion vs 0.9% saline for 4 weeks
Methodological detailssingle-blind, placebo-controlled, matched RYGB cohort for comparison
- Single-blind
- Placebo-controlled
- Matched RYGB cohort for comparison
Primary result
As reported in the abstract
Food preferences, sweet taste function and eating behaviour · 4 weeks
Mean daily energy intake reduced with GOP
27%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Tripeptide gut hormone infusion does not alter food preferences or sweet taste function in volunteers with obesity and prediabetes/diabetes but promotes restraint eating: A secondary analysis of a randomized single‐blind placebo‐controlled study. Diabetes Obes Metab. Published 13 March 2023. doi:10. 1111/ dom. 15028
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