Triglyceride-glucose index in the prediction of clinical outcomes after successful recanalization for coronary chronic total occlusions
Main finding · MACCEResult — go to the resultHazard ratio 1.61 95% CI 1.22–2.12Authors' conclusion
The TyG index demonstrates independent predictive capabilities for MACCE in patients who have undergone successful CTO-PCI. These findings suggest that TyG holds the potential as a valuable tool in risk stratification and the identification of patients who may benefit from early intervention in the management of CTO.
Study context
- Population
- Patients with ≥1 successful percutaneous coronary intervention (PCI) for coronary chronic total occlusion (CTO-PCI)consecutive
- Participants
- 331 patients
- Exposure
- TyG tertiles and per SD increase
- Outcome
- MACCE: mortality, target vessel revascularization, recurrent MI and stroke
- Follow-up
- 32 to 79 months, median 44 months (IQR 39 to 67)
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
MACCE
Hazard ratio
1.61
95% CI 1.22–2.12
TyG per SD increase
HR 1.61 (95% CI 1.22–2.12)
Per SD increase, as printed
As reported in the abstract
- HR for major adverse cardiac and cerebrovascular events (MACCE) in TyG tertile 3, partially adjusted model
- 2.54 (95% CI 1.12-5.79)
- MACCE-free survival differed across TyG tertiles (Kaplan-Meier, log-rank)
- P = 0.001
Observational data: associations, not effects.
Further findings
Predictive ability of TyG for MACCE (ROC)
- AUC
- 0.677
Original publication
Triglyceride-glucose index in the prediction of clinical outcomes after successful recanalization for coronary chronic total occlusions. Cardiovasc Diabetol. Published 8 November 2023. doi:10.
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