Association between the triglyceride-glucose index and 1-year major adverse cardiovascular events in patients with coronary heart disease and hypertension
Authors' conclusion
This study shows that the elevated TyG index is a potential marker of adverse prognosis among patients with CHD and hypertension and informs the development of clinical decisions to improve outcomes.
Study context
- Population
- Patients with coronary heart disease and hypertension admitted to China-Japan Friendship Hospital, 2019–2022; median triglyceride-glucose (TyG) index 8.85 (8.48, 9.18)
- Participants
- 810 patients
- Exposure
- TyG index quartiles Q2, Q3, Q4 vs lowest quartile
- Outcome
- MACE
- Follow-up
- 1 year
Methodological detailssingle-centre, hospital information system database
- Single-centre
- Hospital information system database
Main finding
As reported in the abstract
Odds ratio (95% CI)
Q2vs Q1
1.001(0.986 ≈1.016)
Q3vs Q1
1.047(1.032 ≈1.062)
Q4vs Q1
1.760(1.268 ≈2.444)
- TyG index nonlinearly associated with 1-year MACE risk (restricted cubic spline (RCS))
- P for nonlinear < 0.001
Observational data: associations, not effects.
Further findings
- Results in subgroup analysis similar to main analyses
Original publication
Association between the triglyceride-glucose index and 1-year major adverse cardiovascular events in patients with coronary heart disease and hypertension. Cardiovasc Diabetol. Published 8 November 2023. doi:10.
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