Trends in the incidence of type 1 diabetes and type 2 diabetes in children and adolescents in North Rhine-Westphalia, Germany, from 2002 to 2022
Authors' conclusion
The incidence rates of T1DM and T2DM have increased over the past 20 years, with a wave-like pattern during the Covid-19 pandemic.
Study context
- Population
- Children and adolescents <20 years in North Rhine-Westphalia, Germany (18 million inhabitants), 2002–2022
- Participants
- 17,470 vs 819
- Exposure
- T1DM vs T2DM
- T1DMn = 17,470
- T2DMn = 819
- Outcome
- Direct age- and/or sex-standardized incidence rates per 100,000 PYs and trends as annual percentage changes (APCs)
- Follow-up
- 2002–2022
Methodological detailspopulation-based registry, joinpoint regression
- Population-based registry
- Joinpoint regression
Main finding
As reported in the abstract
Standardized incidence per 100,000 PYs and APC · 2002 to 2022
- T1D standardized incidence, 2002
- 17.6 [16.3;18.9}
- T1D standardized incidence, 2022
- 33.2 [31.3;35.1]
- T1D APC
- 2.7 % [2.3 %;3.1 %]
- T2D standardized incidence, 2002
- 1.3 [0.8;1.7]
- T2D standardized incidence, 2022
- 2.8 [2.0;3.6]
- T2D APC
- 6.4 % [4.9 %;8.0 %]
Observational data: associations, not effects.
Further findings
Segmented trends (joinpoint)
- Four different segmented trends for T1D and T2D, incidence peaking in 2021 and subsequently declining
Person-years and coverage
- Total person-years (PYs), T1D
- 73,743,982
- Total PYs, T2D
- 39,210,453
- Mean coverage rate, T1D
- 98 %
- Mean coverage rate, T2D
- 90 %
Original publication
Trends in the incidence of type 1 diabetes and type 2 diabetes in children and adolescents in North Rhine-Westphalia, Germany, from 2002 to 2022. Diabetes Metab. Published 31 July 2024. doi:10.
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