Trends in respiratory mortality among older U.S. adults with diabetes, 1999–2023
Authors' conclusion
These findings highlight evolving respiratory mortality patterns and underscore the importance of continued surveillance and targeted prevention strategies for older adults with diabetes.
Study context
- Population
- U.S. adults aged ≥65 years with DM listed as a contributing cause of death, 1999–2023
- Outcome
- Respiratory-related AAMR trends
- Follow-up
- 1999–2023
Methodological detailsnationally representative mortality data, Joinpoint regression
- Nationally representative mortality data
- Joinpoint regression
Main finding
As reported in the abstract
Respiratory disease AAMR · 1999 to 2023
Age-adjusted mortality rate (AAMR) remained relatively stable, 1999 to 2023 (per 100,000)
29.24 to 31.21
AAPC
0.19%
APC 1999–2005
+2.60%
initial rise; 95% CI 0.60 to 4.63P < 0.05
APC 2005–2023
−0.60%
sustained decline; 95% CI −0.92 to - 0.28P < 0.001
Observational data: associations, not effects.
Further findings
Rank of respiratory diseases among causes of death
- Respiratory diseases rose from 9th to 6th leading cause of death
Respiratory causes
- Chronic lower respiratory diseases were the leading cause, followed by pneumonia and interstitial lung diseases
Sex and geography
- Mortality consistently higher among men, with substantial geographic variation
Original publication
Trends in respiratory mortality among older U.S. adults with diabetes, 1999–2023. Diabetes Res Clin Pract. Published 29 March 2026. doi:10.
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