Trends in papillary thyroid cancer mortality in Denmark according to stage and education
Authors' conclusion
A pattern of an increasing relative survival and decreasing mortality rates of PTC across all stages was seen in Denmark during 2000-2015. The decreasing pattern in mortality rates was most evident in individuals with localized stage and medium education, and in individuals with nonlocalized stage and medium or long education.
Study context
- Population
- Patients diagnosed with papillary thyroid cancer (PTC) during 2000–2015 in Denmark, followed until end of 2020
- Participants
- 2,006 patients
- Exposure
- 5-year mortality trends by stage and education
- Outcome
- 5-year all-cause mortality and relative survival by stage; 5-year mortality rates with average annual percentage changes (AAPCs) by stage and education
- Follow-up
- 5-year
Methodological detailsDanish Cancer Registry
- Danish Cancer Registry
Main finding
As reported in the abstract
Localized PTC, medium education: AAPC
−7.0
95% CI −14.7 to 1.5
Localized PTC, long education: AAPC (95% CI −4.2 to 50.0), increasing pattern
19.8
Nonlocalized PTC, medium education: AAPC
−5.5
95% CI −13.2 to 2.9
Nonlocalized PTC, long education: AAPC
−10.4
95% CI −20.8 to 1.4
Observational data: associations, not effects.
Further findings
Factors associated with mortality (Cox regression)
- More recent calendar period of diagnosis and long education associated with lower mortality rate
Original publication
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