Trends in hospitalization for cardio‐renal disease and mortality in people with type 1 diabetes in England, 2009–2019
Authors' conclusion
Between 2009 and 2019, hospitalizations for cardiovascular disease increased at younger ages (20-74 years) and hospitalizations for kidney disease increased at all ages, but mortality from cardiovascular and kidney disease declined. All-cause mortality rates were unchanged.
Study context
- Population
- People in England with T1D aged ≥20 years, National Diabetes Audit (2006/2007 to 2016/2017)
- Exposure
- Trends over time, 2009–2019
- Outcome
- Mortality and complication (hospitalization) trends
- Follow-up
- 2009-2019
Methodological detailssequential cohorts, National Diabetes Audit, discretized Poisson regression adjusted for age, sex, ethnicity, socioeconomic deprivation and duration of diabetes
- Sequential cohorts
- National Diabetes Audit
- Discretized Poisson regression adjusted for age, sex, ethnicity, socioeconomic deprivation and duration of diabetes
Main finding
As reported in the abstract
Composite CVD hospitalizations, younger people (increased): RR
1.07
95% CI 1.03–1.11
Composite CVD hospitalizations, elderly (declined): RR
0.91
95% CI 0.86–0.95
Observational data: associations, not effects.
Further findings
All-cause mortality by ethnicity and deprivation
- Younger Asian and Black people had lower all-cause mortality than White; elderly Mixed, Asian and Black people had lower all-cause mortality
- More deprived areas had higher all-cause mortality; deprivation gradient steeper at younger ages
Original publication
Trends in hospitalization for cardio‐renal disease and mortality in people with type 1 diabetes in England, 2009–2019. Diabetes Obes Metab. Published 5 August 2024. doi:10.
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