Trends in admissions for hyperglycaemic emergencies and associated clinical factors in adults with type 2 diabetes in Singapore, 2013–2022
Authors' conclusion
DKA and HHS admission rates rose despite improving HbA1c. High-risk groups may require closer monitoring and targeted interventions.
Study context
- Population
- Adults (≥18 years) with T2D at a tertiary hospital in Singapore, 2013–2022
- Participants
- 47,489 adults
- Comparison
- Higher vs lower HbA1c for diabetic ketoacidosis (DKA)/hyperglycaemic hyperosmolar state (HHS) admission
- Outcome
- Odds of admission for DKA and/or HHS by HbA1c
Methodological detailssingle-centre (tertiary hospital), 1:2 incidence-density matched
- Single-centre (tertiary hospital)
- 1:2 incidence-density matched
Main finding
As reported in the abstract
Admission for DKA and/or HHS
Higher HbA1c associated with admission odds, OR
1.18 (1.13-1.23) (95% CI)
Observational data: associations, not effects.
Further findings
Other independent risk factors for DKA/HHS admission
- Younger age, OR
- 0.72 (0.70-0.74) (95% CI)
- Lower BMI, OR
- 0.96 (0.95-0.98) (95% CI)
- Social housing, OR
- 1.50 (1.13-1.98) (95% CI)
- Diabetes duration >10 years, OR
- 1.58 (1.14-2.21) (95% CI)
- CKD stage ≥3A, highest in stage 4, OR
- 5.81 (4.13-8.17) (95% CI)
Original publication
Trends in admissions for hyperglycaemic emergencies and associated clinical factors in adults with type 2 diabetes in Singapore, 2013–2022. Diabet Med. Published 9 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →