Treatment Satisfaction and Well-Being With Continuous Glucose Monitoring in People With Type 1 Diabetes: An Analysis Based on the GOLD Randomized Trial
Authors' conclusion
While CGM improves glucose control in people with T1D on MDI, increased convenience and flexibility through CGM is of even greater importance for treatment satisfaction and patient well-being. These CGM-mediated effects should be taken into account when considering CGM initiation.
Study context
- Population
- People with T1D managed with MDI
- Participants
- 139 people
- Comparison
- Continuous glucose monitoring (CGM) vs self-monitored blood glucose (SMBG)
Methodological detailscrossover, multivariable R2-decomposition, 16 months
- Crossover
- Multivariable R2-decomposition
- 16 months
Primary result
As reported in the abstract
Contributors to improvement in treatment satisfaction (DTSQc) with CGM
Increased convenience and flexibility: share of DTSQc improvement
60%
95% CI 50%–69%
Perceived effects on hypoglycaemia and hyperglycaemia: share of DTSQc improvement
6%
95% CI 2%–11%
Further findings
| Outcome | P value |
|---|---|
| Well-being (WHO-5) items improved with CGMCGM vs SMBG | P = 0.025 |
| Well-being (WHO-5) items improved with CGMCGM vs SMBG | P = 0.024 |
| Well-being (WHO-5) items improved with CGMCGM vs SMBG | P = 0.046 |
| Well-being (WHO-5) items improved with CGMCGM vs SMBG | P = 0.044 |
Glucose metrics and treatment satisfaction / well-being
- HbA1c reductions and increased time in range (TIR) associated with increased treatment satisfaction; glycemic variability was not
- HbA1c reduction associated with increased well-being; increased TIR with less diabetes-related distress
Original publication
Treatment Satisfaction and Well-Being With Continuous Glucose Monitoring in People With Type 1 Diabetes: An Analysis Based on the GOLD Randomized Trial. J Diabetes Sci Technol. Published 27 July 2023. doi:10.
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