Evaluation of Effects of Continuous Glucose Monitoring on Physical Activity Habits and Blood Lipid Levels in Persons With Type 1 Diabetes Managed With Multiple Daily Insulin Injections: An Analysis Based on the GOLD Randomized Trial (GOLD 8)
Authors' conclusion
Although many patients experience it easier to perform physical activity when monitoring glucose levels with CGM, it does not influence the amount of physical activity in persons with type 1 diabetes. Blood lipids, apolipoprotein, and hsCRP levels were similar during CGM and SMBG.
Study context
- Population
- Patients with T1D managed with MDI
- Comparison
- Continuous glucose monitoring (CGM) vs self-monitoring of blood glucose (SMBG)
Methodological detailscross-over, 4-month wash-out between the two 6-month treatment periods; 16-month trial
- Cross-over
- 4-month wash-out between the two 6-month treatment periods; 16-month trial
Primary result
As reported in the abstract
Physical activity (International Physical Activity Questionnaire (IPAQ) score)
- No changes in physical activity during CGM or SMBG
- CGM vs SMBG: P = 0.16
Further findings
| Outcome | Difference (mmol/mol) | P value |
|---|---|---|
| HbA1c | 4.2 | P < 0.001 |
- HbA1c: NGSP 0.39%; 136 participants with no change in lipid-lowering medication
Blood lipids, apolipoproteins and high-sensitivity C-reactive protein (hsCRP)
- No significant changes in LDL, HDL, triglycerides, total cholesterol, apolipoprotein A1, apolipoprotein B1 or hsCRP during CGM and SMBG
Original publication
Evaluation of Effects of Continuous Glucose Monitoring on Physical Activity Habits and Blood Lipid Levels in Persons With Type 1 Diabetes Managed With Multiple Daily Insulin Injections: An Analysis Based on the GOLD Randomized Trial (GOLD 8). J Diabetes Sci Technol. Published 8 June 2022. doi:10.
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