Time in Range Analysis in Automated Insulin Delivery Era: Should Day and Nighttime Targets be the Same?
Main finding · TIRResult — go to the resultMean percentage difference −8.4%Authors' conclusion
Currently, meeting the conventional TIR metrics may fall short of achieving an ideal level of glycemic control. An individualized strategy should be adopted until further data become available for a precise definition of optimal glucose targets.
Study context
- Population
- Adults with T1D using HCL (Tandem t:slim X2 Control-IQ); mean age 49.7 years, diabetes duration 24.7 years; 14 days Dexcom G6 CGM data
- Participants
- 22 adults
- Exposure
- Conventional time in range (TIR) (70–180 mg/dL) vs recalculated TIR (recalculated time in range (RTIR)) with tighter nighttime fasting target (70–140 mg/dL)
- Outcome
- TIR
Main finding
As reported in the abstract
Mean percentage difference
−8.4%
By group
Observational data: associations, not effects.
Further findings
Correlation between percentage difference and RTIR
- No significant correlation, even among patients with the lowest conventional TIR
Original publication
Time in Range Analysis in Automated Insulin Delivery Era: Should Day and Nighttime Targets be the Same? J Diabetes Sci Technol. Published 19 March 2024. doi:10.
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