The effect of bolus advisors on glycaemic parameters in adults with diabetes on intensive insulin therapy: A systematic review with meta‐analysis
Authors' conclusion
Use of a bolus advisor is associated with slightly better glucose control and treatment satisfaction in people with diabetes on intensive insulin treatment. Future studies should investigate whether personalizing bolus advisors using artificial intelligence technology can enhance these effects.
Study context
- Population
- Adults with diabetes on intensive insulin therapy; 50% females, median HbA1c 8.45% (7.95%-9.30%); mostly T1D (N = 1510, 92%) and MDI (N = 1173, 71%)
- Participants
- 1,645 adults18 randomized controlled trials (RCTs)
- Comparison
- Bolus advisor vs standard treatment
- Outcome
- HbA1c
Methodological detailsrandom-effects model, meta-regression, Risk of bias: 12 of 18 trials low risk (revised Cochrane RoB tool)
- Random-effects model
- Meta-regression
- Risk of bias: 12 of 18 trials low risk (revised Cochrane RoB tool)
Pooled result
As reported in the abstract
MD
−011 %
95% CI −0.22 to −0.01
Further pooled results
Low blood glucose index and treatment satisfaction
- Small improvements in low blood glucose index and treatment satisfaction with bolus advisor
Hypoglycaemic events and other secondary outcomes
- No reductions in hypoglycaemic events or changes in other secondary outcomes
Original publication
The effect of bolus advisors on glycaemic parameters in adults with diabetes on intensive insulin therapy: A systematic review with meta‐analysis. Diabetes Obes Metab. Published 19 March 2024. doi:10.
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