Gestational diabetes & diabetes in pregnancy

The use of machine learning to predict pharmacological therapy in gestational diabetes: A scoping review

Diabet MedPublished Scoping review

Authors' conclusion

Logistic regression with common clinical variables was often used to predict pharmacological therapy for GDM. Few models were externally validated or clinically applicable.

Study context

Population
Studies predicting pharmacological therapy for gestational diabetes mellitus (GDM) using machine learning; Embase, Medline, IEEE Xplore and Web of Science, 1 July 2007–31 August 202417 studies · 44 models
Outcome
Machine learning models predicting pharmacological therapy in GDM
Methodological detailsPRISMA-ScR, Joanna Briggs Institute methodology, PROBAST quality assessment
  • PRISMA-ScR
  • Joanna Briggs Institute methodology
  • PROBAST quality assessment

Main finding

As reported in the abstract

Models predicting any pharmacological therapy use

61.4%

27/44

Models predicting insulin use alone

38.6%

17/44

Overall AUC, median

0.75

Models validated; lack of external validation

65.9%

Original publication

The use of machine learning to predict pharmacological therapy in gestational diabetes: A scoping review. Diabet Med. Published 18 November 2025. doi:10.1111/dme.70171

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