Gestational diabetes & diabetes in pregnancy

The Use of Continuous Glucose Monitoring in Comparison to Self-Monitoring of Blood Glucose in Gestational Diabetes: A Systematic Review

J Diabetes Sci TechnolPublished Systematic review

Authors' conclusion

Continuous glucose monitoring offers substantial advantages over SMBG for managing GDM by providing continuous, real-time glucose data, enabling timely treatment adjustments. These findings support the integration of CGM into clinical practice to improve maternal and neonatal outcomes in GDM. Further research is needed to establish standardized CGM metrics specific to GDM management.

Study context

Population
Women with gestational diabetes mellitus (GDM); RCTs, observational and prospective cohort studies comparing continuous glucose monitoring (CGM) and self-monitoring of blood glucose (SMBG)35 studies
Comparison
CGM vs SMBG
Outcome
Glycemic control: key glycemic metrics such as TIR and glycemic variability (GV), and their associations with maternal and neonatal outcomes
Methodological detailsPRISMA guidelines, PubMed and Google Scholar search
  • PRISMA guidelines
  • PubMed and Google Scholar search

Pooled result

As reported in the abstract

  • CGM vs SMBG: significant improvements in maintaining time in range (TIR) and reducing glycemic variability (GV)
  • Improvements correlated with favorable maternal and neonatal outcomes, including lower rates of large-for-gestational-age infants, preterm birth and NICU admissions

Further pooled results

Detection of hyperglycemic and hypoglycemic events

CGM detected more hyperglycemic and hypoglycemic events, particularly nocturnal fluctuations

Original publication

The Use of Continuous Glucose Monitoring in Comparison to Self-Monitoring of Blood Glucose in Gestational Diabetes: A Systematic Review. J Diabetes Sci Technol. Published 23 July 2025. doi:10.1177/19322968251357873

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