Gestational diabetes & diabetes in pregnancy

Perinatal Outcomes With Continuous Glucose Monitoring in Gestational Diabetes: A Systematic Review and Meta-Analysis

J Diabetes Sci TechnolPublished Systematic review and meta-analysis of randomised trials

Pooled result · TIRResult — go to the resultMD 2.52 95% CI 1.37–3.67

Authors' conclusion

The CGM use in women with GDM significantly improves time in range and increases the use of pharmacotherapy, but it yields no significant differences in other maternal, neonatal, or glycemic outcomes.

Study context

Population
Women with Gestational Diabetes Mellitus (GDM); RCTs from PubMed, Embase, Cochrane Library and ClinicalTrials.gov up to March 2026
Participants
1,639 women12 studies
Comparison
Continuous glucose monitoring (CGM) vs control in GDM
Outcome
TIR

Pooled result

As reported in the abstract

MD

2.52

95% CI 1.37–3.67

CGMvs Control
MD 2.52 (95% CI 1.37–3.67)

Further pooled results

OutcomeRR (95% CI)
Women requiring pharmacotherapy1.15 (1.01–1.32)

Maternal hemoglobin A1c (HbA1c)

No significant difference in maternal HbA1c; MD
−0.11 (−0.24 to 0.01) (95% CI)

Cesarean section

No significant difference in cesarean section; RR
0.97 (0.85 to 1.10) (95% CI)

Large for gestational age

No significant difference in large for gestational age; RR
0.64 (0.40 to 1.02) (95% CI)

Macrosomia

No significant difference in macrosomia; RR
1.13 (0.73 to 1.74) (95% CI)

Neonatal hypoglycemia

No significant difference in neonatal hypoglycemia; RR
0.86 (0.67 to 1.11) (95% CI)

Original publication

Perinatal Outcomes With Continuous Glucose Monitoring in Gestational Diabetes: A Systematic Review and Meta-Analysis. J Diabetes Sci Technol. Published 22 May 2026. doi:10.1177/19322968261443538

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