The triglyceride-glucose index: a novel predictor of stroke and all-cause mortality in liver transplantation recipients
Main finding · Post-LT strokeResult — go to the resultAdjusted odds ratio 3.398 95% CI 1.371–8.426Authors' conclusion
The TyG index may be a valuable and reliable indicator for assessing stroke risk and all-cause mortality in patients undergoing LT, suggesting its potential relevance in improving risk stratification during the peri-LT period.
Study context
- Population
- Patients who underwent liver transplantation (LT) at a university-based medical centre, January 2015–January 2021; median triglyceride-glucose (TyG) index 8.23 (7.78–8.72), 87.18% males780 included
- Participants
- 959 patients
- Exposure
- TyG index tertiles
- Outcome
- Post-LT stroke
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Adjusted odds ratio
3.398
95% CI 1.371–8.426
P = 0. 008
TyG index
aOR 3.398 (95% CI 1.371–8.426); P = 0. 008
- Incidence of post-LT stroke
- 5.38%
- Linear increase in postoperative stroke risk with elevated TyG index on RCS analysis
- P for nonlinearity = 0.480
Observational data: associations, not effects.
Further findings
In-hospital mortality
- In-hospital mortality rate
- 5.54%
- Multivariate regression analysis
1-year mortality
- 1-year mortality rate
- 13.21%
- Multivariate regression analysis
3-year mortality
- 3-year mortality rate
- 15.77%
- Multivariate regression analysis
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The triglyceride-glucose index: a novel predictor of stroke and all-cause mortality in liver transplantation recipients. Cardiovasc Diabetol. Published 13 January 2024. doi:10.
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