The role of body mass index on the association between the energy-adjusted dietary inflammatory index and hyperuricemia: a mediation analysis based on National Health and Nutrition Examination Survey (NHANES) (2007–2016)
Authors' conclusion
E-DII is associated with hyperuricemia. BMI mediates the relationship between E-DII and hyperuricemia among Americans, which provides crucial information for the prevention of hyperuricemia.
Study context
- Population
- American population, NHANES 2007–2016NHANES 2007–2016
- Participants
- 10,571 participants
- Exposure
- Higher vs lower E-DII
- Outcome
- Hyperuricemia
Methodological detailsweighted logistic regression, generalized additive model, mediation analysis
- Weighted logistic regression
- Generalized additive model
- Mediation analysis
Main finding
As reported in the abstract
- Higher E-DII was related to an increased risk of hyperuricemia
- Association between E-DII and hyperuricemia partially mediated by body mass index (BMI)
Observational data: associations, not effects.
Original publication
The role of body mass index on the association between the energy-adjusted dietary inflammatory index and hyperuricemia: a mediation analysis based on NHANES (2007–2016). Int J Obes (Lond). Published 21 November 2023. doi:10. 1038/ s41366-023-01418-x
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