The role of body mass index on the association between the energy-adjusted dietary inflammatory index and hyperuricemia: a mediation analysis based on National Health and Nutrition Examination Survey (NHANES) (2007–2016)

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

E-DII is associated with hyperuricemia. BMI mediates the relationship between E-DII and hyperuricemia among Americans, which provides crucial information for the prevention of hyperuricemia.

Study context

Population
American population, NHANES 2007–2016NHANES 2007–2016
Participants
10,571 participants
Exposure
Higher vs lower E-DII
Outcome
Hyperuricemia
Methodological detailsweighted logistic regression, generalized additive model, mediation analysis
  • Weighted logistic regression
  • Generalized additive model
  • Mediation analysis

Main finding

As reported in the abstract

  • Higher E-DII was related to an increased risk of hyperuricemia
  • Association between E-DII and hyperuricemia partially mediated by body mass index (BMI)

Observational data: associations, not effects.

Original publication

The role of body mass index on the association between the energy-adjusted dietary inflammatory index and hyperuricemia: a mediation analysis based on NHANES (2007–2016). Int J Obes (Lond). Published 21 November 2023. doi:10.1038/s41366-023-01418-x

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