The Resistance Exercise in Already Active Diabetic Individuals (READI) Randomized Clinical Trial
Primary result · HbA1c changeResult — go to the resultIntergroup difference in change −0.07 95% CI −0.31 to 0.18Authors' conclusion
Adding resistance training did not affect glycemia, but it increased strength and reduced waist circumference, in aerobically active individuals with type 1 diabetes.
Study context
- Population
- Aerobically active individuals with T1D, after a 5-week run-in with diabetes management optimization
- Participants
- 131 individuals
- Comparison
- Resistance exercise vs control in aerobically active T1D
- INTn = 71
- CONn = 60reference
- Primary endpoint
- HbA1c
- Follow-up
- 22 weeks
Methodological details4-center, parallel-group, assessor-blinded, Exercise training 3 times per week at community-based facilities
- 4-center
- Parallel-group
- Assessor-blinded
- Exercise training 3 times per week at community-based facilities
Primary result
HbA1c change
Intergroup difference in change
−0.07
95% CI −0.31 to 0.18
INTvs CON
intergroup difference in change −0.07 (95% CI −0.31 to 0.18)
As reported in the abstract
Secondary outcomes
| Outcome | P value |
|---|---|
| Waist circumference · 6 monthsDecreased more in INT | P = 0.02 |
| Muscular strengthIncreased more in INT | P < 0.001 |
Other variables
- No intergroup differences in any other variables
Safety
- No intergroup differences in hypoglycemia
Original publication
The Resistance Exercise in Already Active Diabetic Individuals (READI) Randomized Clinical Trial. J Clin Endocrinol Metab. Published 2 December 2022. doi:10.
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