The relationship of inflammatory markers Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) with HbA1c in Turkish diabetic patients
Authors' conclusion
In light of our findings, we propose a greater emphasis on routinely measuring inflammatory markers, such as NLR, in order to evaluate the glycemic control in patients with type 2 diabetes. We suggest that inflammatory marker-based approaches may be useful to monitor disease progression and maximize treatment outcomes in type 2 diabetes.
Study context
- Population
- Participants grouped by HbA1c, Ankara Bilkent Training and Research Hospital Clinical Biochemistry Department, December 2023
- Participants
- 136 participants
- Exposure
- NLR and PLR across HbA1c-defined groups: DM vs Pre-DM vs control
- Outcome
- Relationship between HbA1c levels and inflammatory parameters NLR and PLR
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
NLR
- Between DM and Control: P = 0.025
- Between DM and Pre-DM: P = 0.034
Observational data: associations, not effects.
Further findings
- Platelet and PLR levels were not statistically significant in group comparisons
Original publication
The relationship of inflammatory markers NLR and PLR with HbA1c in Turkish diabetic patients. Diabetes Res Clin Pract. Published 29 April 2025. doi:10.
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