The relationship between triglyceride-glucose index and prospective key clinical outcomes in patients hospitalised for coronary artery disease
Authors' conclusion
This study reveals a nonlinear association between the TyG index and both all-cause mortality and MACEs in hospitalized CHD patients with CHD. Assessing the TyG index, particularly focusing on individuals with extremely low or high TyG index values, may enhance risk stratification for adverse outcomes in this patient population.
Study context
- Population
- Patients hospitalised with coronary heart disease
- Participants
- 3,321 patients
- Exposure
- Triglyceride-glucose (TyG) index
- Outcome
- All-cause mortality and MACE
- Follow-up
- 9.4 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
9.4 years
- Deaths
- 759 (22.9%)
- MACE
- 1291 (38.9%)
- MACE: U-shaped nonlinear relationship; HR below TyG 8.62
- HR 0.71, 95% CI 0.50-0.99
- MACE: HR above TyG 8.62
- HR 1.28, 95% CI 1.10-1.48
- All-cause mortality: increased risk only when TyG >8.77
- HR 1.53, 95% CI 1.19-1.96
Observational data: associations, not effects.
Original publication
The relationship between triglyceride-glucose index and prospective key clinical outcomes in patients hospitalised for coronary artery disease. Cardiovasc Diabetol. Published 22 January 2024. doi:10.
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